|Series||Heidelberg science library -- 21|
Hydrogen bonds between the base pairs hold a nucleic acid duplex together, with two hydrogen bonds per A-T pair (or per A-U pair in RNA) and three hydrogen bonds per G-C pair. The B-form of DNA has a prominent major groove and a minor groove tracing the path of the helix (Figure ). Nucleic Acids Nucleic acids are key macromolecules in the continuity of life. They carry the genetic blueprint of a cell and carry instructions for the functioning of the cell. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material found in all living organisms, ranging from. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. The sugar in the nucleotides of RNA is ribose; the one in DNA is 2-deoxyribose. The sequence of nucleotides in a nucleic acid defines the primary structure of the molecule. RNA is a single-chain nucleic acid, whereas DNA possesses two nucleic-acid chains intertwined in a secondary structure called a double helix. The sugar-phosphate backbone.
Nucleic acids are large polymers formed by linking nucleotides together and are found in every cell. Deoxyribonucleic acid (DNA) is the nucleic acid that stores genetic information. If all the DNA in a typical mammalian cell were stretched out end to end, it would extend more than 2 m. • For nucleic acids, tertiary structure refers to the overall three-dimensional shape. • In DNA, tertiary structure arises from supercoiling, which involves double helices being twisted into tighter, more compact shapes. 3) Tertiary Structure. Nucleic acid, naturally occurring chemical compound that is capable of being broken down to yield phosphoric acid, sugars, and a mixture of organic bases (purines and pyrimidines).Nucleic acids are the main information-carrying molecules of the cell, and, by directing the process of protein synthesis, they determine the inherited characteristics of every living thing. Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin istrative overwork and excessive teaching obligations, had asked me to do so.
Chapter Nucleic Acids Types of Nucleic Acids Nucleotides: Building Blocks of Nucleic Acids Primary Nucleic Acid Structure The DNA Double Helix Replication of DNA Molecules Overview of Protein Synthesis Ribonucleic Acids Chemistry at a Glance: DNA Replication Transcription: RNA SynthesisFile Size: KB. The Nucleic Acids Research Database Issue contains papers spanning molecular biology. Among them, 59 are new and 79 are updates describing resources that appeared in the Issue previously. The remaining 10 cover databases most recently published elsewhere. Web Server issue. The web server issue of Nucleic Acids Research is the. Learn nucleic acid structure with free interactive flashcards. Choose from different sets of nucleic acid structure flashcards on Quizlet. Nucleic Acid Structure and Recognition will therefore equip readers with a good understanding of all the important aspects of this major field. The Nucleic Acid Database (NDB) crystallographic and NMR structures for the nucleic acid structures described in the book are freely available through the Nucleic Acid Structure and Recognition by: